Correlation between Serum Lipid Profile and Iron Deficiency Anemia in Children in Southeast of Iran

Background: Iron deficiency, is a common worldwide complication, especially in preschool children. Iron deficiency anemia (IDA) is associated with changes in the mental and motor development, defects of immune system, cardiovascular, diseases and disruption of lipid profile. In IDA, the occurrence of dyslipidemia is controversial. We aimed to investigate the association between IDA and serum lipid concentration. Methods: In this comparative cross-sectional study, 41 children with confimed IDA and 39 healthy children were evaluated. Hemoglobin, Hematocrit, serum ferritin level, triglyceride (TG), total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL) and anthropometric indices including weight, height, and body mass index were assessed. Results: The mean±SD age of children with IDA and control group were 10.7±3.5 years and 9.5±3.2 years, respectively (P=0.45). Mean±SD serum lipid profile in control vs IDA groups were as follows: TG (86.1±36.9 vs 88.6±33.5 mg/dl), TC (151.7±28.7 vs 148.9±29.2 mg/dl), LDL (78.4±29.1 vs 88.1±22.6 mg/dl) and HDL (54.2±13.1 vs 52.5±10.1 mg/dl). The results showed no statistically significant difference between IDA and control groups. Slightly increased but not significant TG and LDL levels were observed in the IDA group compared with the control group. Conclusions: Theses findings indicated that there was no significant difference between IDA and control group in terms of serum lipid concentrations.